LMS Technologies Pte Ltd

MP-SPR Navi™ 220A NAALI

The MP-SPR Navi™ 220A NAALI stands as a highly versatile MP-SPR instrument, designed for comprehensive interaction and layer characterization. Its fully automated platform, supporting 96/384-well plates, enables high-throughput analysis. Equipped with up to four wavelengths, it ensures precise layer characterization. A wide array of add-on modules, including electrochemistry, fluorescence, and specialized cell flow cells, expands its application scope. This instrument is ideal for biosensor development, molecular interaction studies, biocompatibility assessments, biomaterial analysis, and live cell research. Its automation and modularity make it a powerful tool for diverse scientific investigations.
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Features

  • Automation of samples from 96 and 384 well plates allows for unattended runs
  • Software switch for serial and parallel injections
  • Partial loop injections providing minimal sample consumption
  • Simultaneous measurements in 2 fluidic channels
  • Two independent wavelength measurements in each fluidic channel, enabling detection of thickness and refractive index or conformational changes
  • Instrument can be equipped optically with up to 4 different wavelenghts measured from each liquid channel for optimal data for layer characterization
  • Exceptionally wide angular range 40˚ – 78˚ enables measurements of small organic molecules and large proteins, but also metallic nanoparticles and cells. Most importantly, it enables in-line bulk effect separation with PureKinetics™
  • Measurements of kinetic constants, concentration and competition analysis, affinity and EC50
  • Controlled buffer flow conditions with precise syringe pumps and integrated degasser
  • Software package for convenient control of the instrument and easy analysis of the results. The instrument comes with TraceDrawer™ for MP-SPR Navi™ – a powerful software for the determination of affinity and kinetic constants and more. MP-SPR Navi™ LayerSolver for the determination of thickness and RI from multiple wavelength measurements is an optional module
  • MP-SPR Navi™ instruments utilize optical RI matching elastomer and therefore, sensors are very easy to exchange and remove for further analysis with other methods such as AFM or microscopy
  • Complement with electrochemistry, high chemical resistant and gas flow cells as well as fluorescence setup provides combined or validation measurements