MP-SPR Navi™ 410A KAURIS
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Features
- 4 fluidic channels for high throughput
- Automated liquid handling of up to 7 different samples for unattended runs
- Software switch for serial and individual injections
- Partial loop injections enabling minimized sample consumption
- KineticTitration for faster interaction affinity and kinetic measurements
- Two independent wavelength measurements in each fluidic channel, enabling detection of thickness and refractive index or conformation changes
- Exceptionally wide angular range 40˚ – 78˚ enables measurements of small organic molecules and large proteins, but also nanoparticles and cells. Most importantly, it enables in line bulk effect separation PureKinetics™
- Controlled buffer flow conditions with precise syringe pumps and integrated degasser
- Software package for convenient control of the instrument and easy analysis of the results. The instrument comes with TraceDrawer for MP-SPR Navi™, a powerful software for concentration analysis and determination of affinity and kinetics of interactions. MP-SPR Navi™ LayerSolver is optional and enables to determine thickness and refractive index from multiple wavelength measurements
- MP-SPR Navi™ instruments utilize optical RI matching elastomer and therefore, sensors are very easy to exchange and also to further analyze with other methods such as AFM or microscopy
- Open design enables convenient access to the easily removable flow cell, as well as to tubing, pump and injection valves
| Number of fluidic channels | 4 |
| Autosampler for liquids | 7-vials |
| Unattended run | Yes |
| Buffer degasser | Yes |
| Syringe pumps | Yes |
| Kinetic Titration | Yes |
| Wavelengths in each measurement channels | 2 |
| Please see the Bionavis website for a series of application notes |  |
Flow-cells
We provide a range of application-specific, user-replaceable flow cells. Standard materials include PDMS, PEEK, and Kalrez, tailored for kinetic or material characterization. Specialized cells combine MP-SPR with electrochemistry, fluorescence, or live-cell studies. All support air/liquid, with a gas cell for pressurized gas.
MP-SPR Navi™ Immobilizer
Our MP-SPR Navi™ Immobilizer is a specialized stand-alone holder for chemical modification and functionalization of sensor surfaces, compatible with MP-SPR Navi™ sensor slides and slide holders.
More information in Application Note #130 >>>
Additional wavelengths
Simultaneous multi-wavelength SPR measurements, using two to four wavelengths, provide accurate thickness and refractive index data. Three or four wavelengths remove the need for additional assumptions. This technique is vital for material characterization, vesicle analysis, and live cell studies. Navi™ instruments support two wavelengths, while the OTSO, VASA, and NAALI models offer four.
MP-SPR sensor slides
BioNavis provides high-quality MP-SPR sensor slides, compatible with all Navi™ instruments, for precise measurements. Our diverse range caters to various applications. The user-friendly slide holder simplifies ex situ functionalization via spin coating, Lb, self-assembly, CVD, or ALD.
Browse BioNavis for sensor surfaces matching your needs: https://bionavis.com/products/sensor-slides