LMS Technologies Pte Ltd

Leica - K8
The Scientific CMOS Camera

For Life Science Imaging Applications and Analysis

The Leica K8 Scientific CMOS microscope camera is a cutting-edge solution for the most challenging live-cell experiments. It uses a 95% quantum efficiency (QE) back-thinned CMOS sensor to capture more data from your sample, even in extreme low light imaging conditions.

The K8 can capture razor-sharp THUNDER images, allowing you to realize the full potential of your system. Its combination of extremely low read noise, minimal sensor artifacts, and high QE allows you to extract quantifiable data from your sample while exposing it to the minimum of phototoxicity.

With the K8, you can push the limits of your experiments and capture stunning high-resolution images, track subcellular organelles in extreme low light, or image high-speed cellular processes. The K8 can handle a wide range of challenging applications.
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Capture more data* from your sample

Live cells respond by activating stress pathways when they are exposed to the high-intensity light that is typically used for fluorescent imaging.

The K8 camera’s increased camera sensitivity makes it possible to use lower light doses* to capture images, thus improving cell viability and allowing you to extract meaningful data from your sample for longer.

The K8 camera’s market-leading 95% QE sensor offers exceptional photon detection, allowing you to push your experiment further.

*Than achievable with legacy 80% QE CMOS cameras.

Razor-sharp THUNDER images even in extreme low light conditions

Unlike fixed samples, where users typically need to take a single image of a sample stained with photo stable dyes, live-cell imaging experiments require hundreds or even thousands of images of a photo sensitive sample to acquire a time lapse sequence. In order to get relevant results, it often becomes necessary to use much shorter exposures and lower excitation intensities to prevent photo damaging the sample, resulting in low signal to noise ratio (SNR) images.

The less light you work with on your samples, the lower the SNRs, and this is when the K8 camera truly displays its cutting-edge power, delivering razor sharp images even in extreme low light conditions. The K8 camera empowers your research through computationally enhanced THUNDER images with reduced artefacts at even lower light levels than previously possible.

Push the limits of your experiments

Take advantage of AI-enhanced clarity and accuracy enabled through the powerful combination of THUNDER and Aivia to analyze fluorescent images with greater accuracy, even when using low light excitation.

Leica offers a unique trilogy of technologies in the form of the K8 scientific CMOS microscope camera, THUNDER and Aivia that enables you to truly push the limits of your research while still extracting high quality quantifiable data from the images.

TECHNICAL SPECIFICATIONS

Sensor type Scientific CMOS
Senosr size (diagonal). 18.8 mm
Sensor format 2048 px x 2048 px (4.2 Megapixel)
Pixel dimensions 6.5 μm x 6.5 μm
Shutter mode Rolling shutter
Data interface USB 3 Gen2
Mechanical interface C-mount
Exposure range 1 ms - 10 s
Frames per second 95 fps (in 11-bit mode)
Triggering Yes, MMCX
Sensor cooling -5 °C at 25 °C ambient
Peak quantum efficiency 95%
Dark current 1.5 e-/pixel/second
Read noise 12-bit 1.0 e- (median) 1.1 e- (RMS)16-bit 1.6 e- (median) 1.8 e- (RMS)
Full well capacity 45000 e-
Dynamic Range 25000:1
Bit depth / Colour depth 16-bit, 12-bit, 11-bit, 8-bit
Binning options 2x2
Operating system Windows with LAS X application
Power consumption 60 W
Operation temperature 5 °C - 40 °C
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