Wyatt instruments provides a range of multi-angle light scattering (MALS) detectors that can be interfaced with any SEC (Size Exclusion Chromatography) system for effective means for absolute characterization of proteins, polymer, biopolymer and synthetic polymer. MALS measures molecular weight and rms radius (a.k.a. radius of gyration) directly from first principles independent of retention time, molecular standards and regardless of non-ideal column interactions.

Static Light Scattering Products


The miniDAWN® determines absolute molar mass and size to characterize proteins, peptides, small polymers and nanoparticles in solution. Coupled to size exclusion chromatography (SEC or GPC), it eliminates the uncertainty and hassle of column calibration, for true confidence in macromolecular characterization.

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The DAWN® is the premier Multi-Angle static Light Scattering (MALS) detector for absolute characterization of the molar mass and size of macromolecules and nanoparticles in solution. The DAWN® offers the highest sensitivity, the widest range of molecular weight, size and concentration, and the largest selection of configurations and optional modules for enhanced capabilities.

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The  microDAWN™ can be coupled to any UHPLC-SEC system to determine absolute molecular weights and sizes of polymers, peptides, or proteins directly, without resorting to column calibration or reference standards. The  microDAWN™ produces minimal band broadening in order to maintain the narrow peaks typical of UHPLC, while meeting or exceeding the sensitivity of the miniDAWN®.

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