Refractometers

Optilab®


The Optilab® (refractometer with EXtended range) is a unique dRI detector for standard HPLC/GPC with 256 times the detection power and 50 times the dynamic range of every other RI detector for chromatography in existence today, making it a valuable addition to any MALS setup.

The Optilab® can also do something no other on-line refractive index detector can: it can measure the absolute refractive index of a solution. In addition, it can measure the dn/dc of a solvent at the same wavelength of light as the light scattering instrument. And just to make sure it can't be matched, you can replace the light source in the Optilab® for other wavelengths (e.g., 690, 633, 488, etc.) in just minutes!

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Optilab®

  • Extraordinary dRI measurement range, -0.0047 - +0.0047 RIU (comparable to 25 mg/mL protein in PBS)
  • Highly sensitive, ±7.5 x 10-10 RIU across the entire measurement range
  • Measures solvent absolute refractive index, required for MALS calculations
  • Measures at the same wavelength as the MALS detector, for maximum accuracy in MALS calculations
  • Band broadening < 20 µL preserves SEC resolution
  • Temperature range 4°C - 65°C for proteins and polymers that require a range of temperatures
  • High-resolution, touch-screen front panel displays data graphs and diagnostics, even with the host computer turned off

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